Sunday, July 12, 2009

VITAMIN C

Vitamin C (Ascorbic Acid)
Vitamin C plays an important role in the formation of collagen.
Vitamin C also aids iron absorption, increases bioavailability of selenium, and may increase the conversion of cholesterol to bile acid.
Vitamin C deficiency (scurvy) usually is seen in individuals with inadequate intake of fresh fruits or vegetables, such as the elderly or those who abuse alcohol. In addition, the human vitamin C requirement is increased by smoking
Clinical manifestations often remain latent for several months following onset of severe vitamin C deficiency. Symptoms begin with body ache tiredeness and weakness.
skin problems start with follicular hyperkeratosis; the associated hair is often coiled or looped (corkscrew hairs). Hairs may be bent at multiple sites, leading to a swan-neck deformity. The main sites affected are the upper arms, back, buttocks, thighs, calves, and shins. Perifollicular purpura follows, particularly on the legs .
Old scars break down, and new wounds heal poorly. swelling of the legs also has been noted, and in the mouth, the gums become red, swollen, and may bleed; gumnecrosis may occur ultimately.
Patients respond quickly to the administration of oral vitamin C (100 mg three times daily). A daily intake of vitamin C in the form of fresh fruits or supplements should be ensured.

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