Riboflavin (vitamin B 2)
is found in milk, meat, fish, and eggs.
Deficiency of riboflavin occurs predominantly by diet of unenriched cereals.
Clinical deficiency usually occurs 3 to 5 months after an inadequate diet.
riboflavin deficiency develops in infants who are not fed milk after being weaned from breast-feeding.
riboflavin deficiency in humans mainly causes skin problems It may affect the mouth, eyes, and genital area and is known as the oro-oculogenital syndrome.
In the mouth, glossitis denudes the papillae and causes the tongue to appear magenta-colored.
Vertical fissures of the lip, termed cheilosis, develop.
A dermatitis similar to seborrheic dermatitis develops along the sides of the nose, cheeks, forehead, and behind the ears.
Eye problems associated with riboflavin deficiency are conjunctivitis and photophobia.
Dermatitis of the genital area may develop, followed by thickening of skin in chronic cases.
In men, dermatitis begins on the scrotum ,It may extend up the penis or onto the inner aspects of the thighs. In women, the vulva is affected..
anemia may occur. In children, retarded intellectual development . riboflavin deficiency usually responds promptly and dramatically to riboflavin supplementation. Therapy is with 1 to 3 mg/day in infants and 10 to 20 mg/day in adults.
Sunday, July 12, 2009
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