Vitamin B1 ( Thiamine)

Vitamin B1
VITAMIN B 1 (THIAMINE) Thiamine pyrophosphate is an enzyme involved in carbohydrate metabolism
Thiamine is obtained in the diet through consumption of poultry, milk, eggs, dry beans, peas, and enriched bread products.
Although it occurs naturally in brown rice and cereal grains, the “polishing” of rice and milling of grain cause it to be lost.
Thiamine deficiency causes two diseases.
In Asia, persons subsisting on polished-rice diets develop beri-beri, a disorder characterized by fatigue, peripheral neuropathy, polyneuritis, heart failure, edema, angular stomatitis, and glossitis.
In the United States, thiamine deficiency mainly results from poor dietary intake in association with alcoholism. This presents as the Wernicke-Korsakoff syndrome, characterized by apathy, loss of memory, and confabulations.
Thiamine replacement is critical. Thiamine deficiency is often seen associated with other B-complex vitamin deficiencies as well as folate deficiency, and broad nutritional support is usually required.